DC1
Host institution: GENAR
Project title: Innovative genomic technologies for the advanced characterization of myotonic dystrophy mutations (WP1).
Host institution: GENAR
Project title: Innovative genomic technologies for the advanced characterization of myotonic dystrophy mutations (WP1).
Host institution: UTOV
Project title: The complexity of DM repeat expansions: new challenges in developing personalized molecular therapeutics (WP1).
Host institution: IBEC
Project title: A new integrated in vitro platform to study DM muscle disease (WP1).
Host institution: CECS
Project title: Advanced human 3D neuromuscular and cortical models for mechanistic and therapeutic research (WP1).
Host institution: RUMC
Project title: Structure and dynamics of nuclear RNA foci in myotonic dystrophy type 1 and 2 (WP1)
Host institution: UVEG
Project title: The contribution of miRNome alterations to DM1: beyond the Muscleblind sequestration model (WP1).
Host institution: RUMC
Project title: Rescuing disrupted single-cell and neural network activities in human DM neural models using ASO (WP2)
Host institution: AMU
Project title: Therapeutical potential of ASO inducing skipping of CUGexp-containing exon in myotonic dystrophy (WP2)
Host institution: UVEG
Project title: Enhancing the activity of therapeutic ASO by genetic modulation and sequence motif adjuvants (WP2).
Host institution: CSIC
Project title: Novel ASO molecules for the therapy of DM1 (WP2)
Host institution: INSERM
Project title: Development of circulating muscle-specific biomarkers (WP3)
Host institution: INSERM
Project title: Circulating biomarkers of brain dysfunction in DM1 (WP3)
Host institution: LMU
Project title: Myotonic Dystrophy Type 2 (DM2): Biomarker discovery and correlation to clinical outcomes (WP3)
Host institution: UPC
Project title: Participation in clinical trials: the contribution of decision-making cognition in patients with DM1 (WP3)